Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | CCR2 | P41597 | 3/20 | 0.52 |
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PDE9A | O76083 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560196 | 0.89 | CNR1 (0.50) | CNR1CCR2CFTRSMN1; SMN2PPARG | |
| SCHEMBL9356151 | 0.86 | P2RX4 (0.52) | HPGDSMN1; SMN2LMNAPPARGALDH1A1 | |
| SCHEMBL28463754 | 0.79 | CCR2 (0.49) | CNR1CCR2CFTRHPGDSMN1; SMN2 | |
| SCHEMBL28346152 | 0.79 | CCR2 (0.49) | CNR1CCR2CFTRHPGDSMN1; SMN2 | |
| SCHEMBL30783420 | 0.78 | HPGD (0.60) | CNR1CCR2CFTRHPGDSMN1; SMN2 | |
| SCHEMBL8802854 | 0.78 | CCR2 (0.54) | CCR2CFTRHPGDSMN1; SMN2LMNA | |
| SCHEMBL29200758 | 0.78 | HPGD (0.60) | CNR1CCR2CFTRHPGDSMN1; SMN2 | |
| SCHEMBL13531041 | 0.76 | CCR2 (0.55) | CNR1CCR2CFTRHPGDSMN1; SMN2 | |
| SCHEMBL9396355 | 0.76 | CCR2 (0.55) | CNR1CCR2CFTRHPGDSMN1; SMN2 | |
| SCHEMBL11536101 | 0.75 | CCR2 (0.66) | CNR1CCR2HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040459-A1 | IMPROVED SOLUBILITY FOR TARGET COMPOUNDS | Aunova Medchem LLC (US) | 2017-03-09 | — | — | WO | disclosed |
| EP-0625144-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015056-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | disclosed |