Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336086 | 0.76 | TTR (0.46) | TTRERN1MAOBTPMTPKM | |
| SCHEMBL8425070 | 0.74 | TTR (0.43) | TTRERN1MAOBTPMTPKM | |
| SCHEMBL9356500 | 0.74 | TTR (0.43) | TTRERN1MAOBTPMTPKM | |
| SCHEMBL10498088 | 0.74 | TTR (0.50) | TTRERN1MAOBTPMTPKM | |
| Hydrochloric Acid SCHEMBL8425075 | 0.74 | TTR (0.43) | TTRERN1MAOBTPMTPKM | |
| Potassium Ion SCHEMBL31229268 | 0.72 | TTR (0.42) | TTRERN1MAOBTPMTPKM | |
| SCHEMBL4078422 | 0.71 | TTR (0.53) | TTRERN1PKM | |
| SCHEMBL9141562 | 0.69 | TTR (0.39) | TTRERN1 | |
| SCHEMBL25477911 | 0.69 | CA12 (0.45) | TTR | |
| SCHEMBL24777111 | 0.69 | TTR (0.44) | TTRERN1MAOBTPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557345-B1 | 1,3-BIS- 3-(MONO- OR POLY-HYDROXY)ACYLAMINO-5-(MONO- OR POLY-HYDROXYALKYL)AMINOCARBONYL-2,4,6-TRIIODO-BENZOYL-AMINO]-HYDROXY- OR HYDROXYALKYL-PROPANES, THEIR METHODS OF PREPARATION AND X-RAY CONTRAST MEDIA CONTAINING THEM | DIBRA SPA (IT) | 1994-09-14 | — | — | EP | disclosed |
| EP-0557345-A1 | 1,3-BIS- 3-(MONO- OR POLY-HYDROXY)ACYLAMINO-5-(MONO- OR POLY-HYDROXYALKYL)AMINOCARBONYL-2,4,6-TRIIODO-BENZOYL-AMINO]-HYDROXY- OR HYDROXYALKYL-PROPANES, THEIR METHODS OF PREPARATION AND X-RAY CONTRAST MEDIA CONTAINING THEM. | DIBRA SPA (IT) | 1993-09-01 | — | — | EP | disclosed |