SCHEMBL2336086

SCHEMBL2336086

O=C(O)c1c(I)cc(I)cc1I

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.46
▸ TPMT P51580 3/20 0.44
▸ MAOB P27338 1/20 0.41
▸ MAPK1 P28482 2/20 0.40
▸ TSHR P16473 1/20 0.40
▸ ERN1 O75460 1/20 0.38
▸ GPR17 Q13304 1/20 0.36
▸ CA12 O43570 1/20 0.35
▸ CA1 P00915 1/20 0.35
▸ CA2 P00918 1/20 0.35
▸ CA7 P43166 1/20 0.35
▸ CA9 Q16790 1/20 0.35
▸ CA14 Q9ULX7 1/20 0.35
▸ CYP1A2 P05177 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ GLA P06280 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8425075 0.97 TTR (0.43) TTRTPMTMAOBMAPK1TSHR
SCHEMBL24777111 0.85 TTR (0.44) TTRTPMTMAOBMAPK1TSHR
SCHEMBL21783817 0.84 CYP3A4 (0.45) TTRTPMTMAOBMAPK1TSHR
SCHEMBL23600932 0.81 CYP3A4 (0.46) TPMTMAPK1TSHRCA12CA1
SCHEMBL4078422 0.79 TTR (0.53) TTRERN1PKM
SCHEMBL25604521 0.79 TPMT (0.48) TPMTMAPK1TSHRALDH1A1KDM4E
SCHEMBL11517880 0.79 TPMT (0.41) TPMTMAPK1TSHRCA12CA1
SCHEMBL377395 0.78 MAPK1 (0.53) TPMTMAPK1TSHRCA12CA1
Metacresol SCHEMBL27702878 0.76 ACHE (0.55) TTRCA12CA1CA2CA7
SCHEMBL9356496 0.76 TTR (0.43) TTRTPMTMAOBERN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631532-A1 PREPARATION METHOD FOR EMBOLIZATION MICROSPHERES Shanghai Intervascular MedTech Co., Ltd. (CN) 2025-10-15 — — EP claimed
WO-2024146444-A1 PREPARATION METHOD FOR EMBOLIZATION MICROSPHERES 上海拓脉医疗科技有限公司 2024-07-11 — — WO claimed
CN-118286496-A Preparation method of embolism microsphere 上海拓脉医疗科技有限公司 2024-07-05 — — CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 — — CN claimed
CN-114057600-B X-ray developable molecule, drug-loaded embolism microsphere and preparation method thereof 上海汇禾医疗科技股份有限公司 2024-02-02 — — CN claimed
CN-116875024-A Hydrogel with X-ray visibility and preparation method and application thereof 赛克赛斯生物科技股份有限公司 2023-10-13 — — CN claimed
EP-2066362-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF Boston Scientific Limited (BB) 2009-06-10 — — EP claimed
WO-2008033198-A1 RADIOPAQUE AMIDE POLYMERS AND MEDICAL DEVICES FORMED THEREOF BOSTON SCIENTIFIC LIMITED (BB) 2008-03-20 — — WO claimed
US-20080064848-A1 Radiopaque amide polymers and medical devices formed thereof BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-03-13 — — US claimed
US-5160725-A Contrast agent for diagnostic imaging, polyethylene glycol phosphates and carboxylates as stabilizers SILICA GEL GESELLSCHAFT MBH ADSORPTIONS-TECHNIK, APPARATEBAU (DE) 1992-11-03 — — US claimed
EP-0284549-B1 MAGNETIC FLUID COMPOSITIONS Silica Gel Ges.mbH Absorptionstechnik, Apparatebau (DE) 1992-07-15 — — EP claimed
EP-0160036-A4 NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA. BIOPHYSICA FOUNDATION (US) 1987-06-11 — — EP claimed
EP-0160036-A1 NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA BIOPHYSICA FOUNDATION (US) 1985-11-06 — — EP claimed
WO-1985001727-A1 NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA BIOPHYSICA FOUNDATION (US) 1985-04-25 — — WO claimed
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 — — US disclosed
US-20260083724-A1 COMPOUNDS TARGETING PAX3::FOXO1 FUSION PROTEIN GEORGETOWN UNIVERSITY (US) 2026-03-26 — — US disclosed
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-02-19 — — US disclosed
US-4021481-A X-RAY CONTRAST AGENTS NYEGAARD & CO. A/S (NO) 1977-05-03 — — US disclosed
US-3953497-A X-RAY CONTRAST AGENTS MALLINCKRODT, INC. (US) 1976-04-27 — — US disclosed
US-3852341-A NOVEL IODINE CONTAINING POLYMERS USEFUL AS X-RAY CONTRAST AGENTS PHARMACIA AB 1974-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115330-A1 RADIOPAQUE MULTI-ARM POLYMERS FOR MEDICAL APPLICATIONS KLK3, BRDT, BPHL TTR 2492/4885TPMT 4080/4885MAOB 4436/4885
US-20260049178-A1 CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM NPPA, MACF1, IGF1R TTR 1860/4885TPMT 3130/4885MAOB 3190/4885
US-20260083724-A1 COMPOUNDS TARGETING PAX3::FOXO1 FUSION PROTEIN PAX3, FOXO1, PAXBP1 TTR 4038/4885TPMT 2264/4885MAOB 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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