Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407764 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TPMT | |
| Hydrochloric Acid SCHEMBL11880989 | 0.78 | THRB (0.33) | ALDH1A1PKM | |
| SCHEMBL793421 | 0.77 | ALDH1A1 (0.52) | TTRALDH1A1 | |
| SCHEMBL34467595 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TPMT | |
| SCHEMBL2336086 | 0.76 | TTR (0.46) | TTRALDH1A1ERN1MAOBTPMT | |
| SCHEMBL31232360 | 0.75 | TPMT (0.39) | ALDH1A1TPMT | |
| SCHEMBL25779937 | 0.75 | TPMT (0.39) | ALDH1A1TPMT | |
| SCHEMBL9356500 | 0.74 | TTR (0.43) | TTRERN1MAOBTPMTPKM | |
| SCHEMBL9356496 | 0.74 | TTR (0.43) | TTRERN1MAOBTPMTPKM | |
| SCHEMBL10498088 | 0.74 | TTR (0.50) | TTRERN1MAOBTPMTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMA CO LTD (JP) | 2022-02-17 | — | — | US | disclosed |
| CN-105348410-B | One kind polysaccharide containing iodine and its synthetic method and application | 中山大学 | 2019-02-26 | — | — | CN | disclosed |
| US-5886169-A | DEXTRAN CONTAINING GRAFTED IODINATED GROUPS; RADIOLOGY CONTRAST AGENTS | GUERBET S.A. (FR) | 1999-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | AOC2, SSTR2, NISCH | TTR 4548/4885ALDH1A1 4215/4885ERN1 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.