Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356888 | 0.92 | KCNK3 (0.41) | ABCB1 | |
| SCHEMBL9357050 | 0.91 | ABCB1 (0.40) | ABCB1 | |
| SCHEMBL9356802 | 0.91 | ABCB1 (0.40) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL9356862 | 0.89 | ABCB1 (0.34) | ABCB1 | |
| SCHEMBL9357534 | 0.88 | ABCB1 (0.39) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL9357214 | 0.88 | ABCB1 (0.46) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL9357277 | 0.88 | ABCB1 (0.47) | ABCB1CYP2C19 | |
| SCHEMBL9356842 | 0.86 | ABCB1 (0.45) | ABCB1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL9356838 | 0.84 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL9357142 | 0.83 | LMNA (0.41) | ABCB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461809-B1 | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1994-12-07 | — | — | EP | claimed |
| EP-0461809-A1 | Dibenzoylalkylcyanohydrazines | ROHM AND HAAS COMPANY (US) | 1991-12-18 | — | — | EP | claimed |