Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356802 | 0.92 | ABCB1 (0.40) | HTTABCB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9356888 | 0.91 | KCNK3 (0.41) | LMNASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9356789 | 0.91 | HPGD (0.39) | LMNASMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9357123 | 0.90 | ABCB1 (0.47) | HTTABCB1HPGDALDH1A1SLC6A2 | |
| SCHEMBL9356815 | 0.89 | TSHR (0.41) | HTTABCB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9357042 | 0.86 | ABCB1 (0.41) | HTTABCB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9356941 | 0.84 | HPGD (0.40) | NPC1RAB9AKCNK3KCNK9ABCB1 | |
| SCHEMBL9854889 | 0.84 | KCNK3 (0.45) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL9356785 | 0.83 | ABCB1 (0.40) | HTTABCB1 | |
| SCHEMBL9356842 | 0.83 | ABCB1 (0.45) | HTTABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461809-B1 | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1994-12-07 | — | — | EP | claimed |