Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 8/20 | 0.49 |
| ▸ | HTR1B | P28222 | 8/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357270 | 0.91 | HTR1A (0.64) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| Sulfuric Acid SCHEMBL9873208 | 0.86 | HTR1A (0.66) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL6890172 | 0.86 | HTR1A (0.65) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL9790402 | 0.85 | HTR1A (0.62) | HTR1AHTR1DHTR1BDRD2 | |
| Hydrochloric Acid SCHEMBL7716614 | 0.85 | HTR1A (0.64) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL10340387 | 0.82 | HTR1A (0.60) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL9558592 | 0.81 | HTR1A (0.75) | HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL9536727 | 0.81 | HTR1A (0.57) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL9531561 | 0.81 | HTR1A (0.59) | HTR1AMTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL7208944 | 0.81 | HTR1A (0.81) | HTR1AHTR1DHTR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392768-B1 | Tetrahydrobenz[C,D] indole serotonin agonists | LILLY CO ELI (US) | 1994-12-07 | — | — | EP | claimed |