Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357374 | 0.85 | MEN1 (0.43) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9850203 | 0.82 | RARB (0.56) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9241187 | 0.80 | RARB (0.50) | RARBHSD17B10KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL19674984 | 0.79 | RARB (0.51) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9357135 | 0.77 | RAB9A (0.59) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL10701933 | 0.76 | ALDH1A1 (0.45) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL9636346 | 0.76 | RARB (0.52) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12622306 | 0.75 | ALDH1A1 (0.63) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL13539888 | 0.75 | ALDH1A1 (0.62) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8402267 | 0.75 | RARB (0.46) | RARBALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289270-B1 | Optically active 2-biphenylpyrimidine derivatives and liquid crystal compositions containing them | CHISSO CORP (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5059340-A | For display mode | CHISSO CORPORATION (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0289270-A1 | Optically active 2-biphenylpyrimidine derivatives and liquid crystal compositions containing them | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |