SCHEMBL9357342

SCHEMBL9357342

C=CC(=O)NCCC=O.COC(C)OC

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
TSHR P16473 3/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TGM2 P21980 2/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3272645 0.89 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL3273544 0.88 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL9501197 0.84
SCHEMBL1292813 0.83 TSHR (0.42) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL7746292 0.83 ZDHHC20 (0.44) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL28462817 0.80 TSHR (0.64) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL9760543 0.80 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL9353958 0.79 TSHR (0.37) TSHRALDH1A1
SCHEMBL3394081 0.74 TSHR (0.43) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Dimethoxymethane SCHEMBL29176148 0.73 ZDHHC20 (0.50) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350277-B1 Temporary wet strength resins and paper products containing same PROCTER & GAMBLE (US) 1994-10-26 EP disclosed
US-5085736-A Temporary wet strength resins and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1992-02-04 US disclosed
EP-0350277-A2 Temporary wet strength resins and paper products containing same THE PROCTER & GAMBLE COMPANY (US) 1990-01-10 EP disclosed