SCHEMBL3394081

SCHEMBL3394081

C=CC(=O)NCOC(C)OC

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
TGM2 P21980 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL644261 0.82 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28462817 0.81 TSHR (0.64) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL8794243 0.78 TSHR (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL7746292 0.76 ZDHHC20 (0.44) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL1292813 0.76 TSHR (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL17727675 0.76 TSHR (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL138455 0.76
Hydrochloric Acid SCHEMBL11792544 0.75 TSHR (0.41) TSHRALDH1A1MAPK1TDP1ZDHHC20
Hydrochloric Acid SCHEMBL11796910 0.75 TSHR (0.41) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL9357342 0.74 ZDHHC20 (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3114164-B1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES INC (US) 2025-07-02 EP disclosed
US-9976055-B2 Lower temperature cure coating compositions KING INDUSTRIES (US) 2018-05-22 US disclosed
US-20150197665-A1 LOWER TEMPERATURE CURE COATING COMPOSITIONS KING INDUSTRIES (US) 2015-07-16 US disclosed
US-20130216723-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2013-08-22 US disclosed
US-8431730-B2 Sulfonate esters as latent acid catalysts KING INDUSTRIES (US) 2013-04-30 US disclosed
EP-2203519-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS King Industries (US) 2010-07-07 EP disclosed
US-20090104363-A1 Sulfonate esters as latent acid catalysts KING INDUSTRIES 2009-04-23 US disclosed
WO-2009045466-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2009-04-09 WO disclosed
US-4477618-A CROSSLINKING AN ACTIVE HYDROGEN-CONTAINING RESIN BLEND BY BAKING; STORAGE STABILITY PPG INDUSTRIES, INC. (US) 1984-10-16 US disclosed
US-4469832-A SPRAYABLE COATINGS PPG INDUSTRIES, INC. (US) 1984-09-04 US disclosed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US disclosed
US-4417022-A SOLVENT-FREE PPG INDUSTRIES, INC. (US) 1983-11-22 US disclosed
US-4343925-A POLYESTERS PPG INDUSTRIES, INC. (US) 1982-08-10 US disclosed
US-4317894-A Low temperature cure coating compositions PPG INDUSTRIES, INC. (US) 1982-03-02 US disclosed
US-4314918-A Coating compositions containing organic alcoholic reactive diluents PPG INDUSTRIES, INC. (US) 1982-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104363-A1 Sulfonate esters as latent acid catalysts ORAI1, SARAF, NAPA TSHR 4219/4885ALDH1A1 3647/4885MAPK1 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.