Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356735 | 0.89 | POLQ (0.47) | POLQHPGDHTTMEN1KMT2A | |
| SCHEMBL9360958 | 0.85 | CTBP2 (0.42) | POLQHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL9356980 | 0.85 | POLQ (0.43) | POLQHPGDHTTMEN1KMT2A | |
| SCHEMBL9356987 | 0.81 | CETP (0.49) | POLQHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL6136371 | 0.81 | MEN1 (0.43) | POLQHPGDHTTMEN1KMT2A | |
| SCHEMBL9357340 | 0.80 | CTBP2 (0.38) | POLQHPGDCYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL9356743 | 0.80 | PPARG (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9357323 | 0.79 | OPRK1 (0.46) | HTTMEN1KMT2AGAACYP1A2 | |
| SCHEMBL9360721 | 0.77 | OPRK1 (0.44) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21518476 | 0.75 | POLQ (0.45) | POLQHPGDHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415185-B1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1994-12-07 | — | — | EP | disclosed |
| EP-0415185-A1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |