Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357340 | 0.91 | CTBP2 (0.38) | CTBP2POLQALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9357397 | 0.85 | POLQ (0.47) | POLQALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL9360988 | 0.81 | LMNA (0.41) | POLQALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL9357000 | 0.78 | ALDH1A1 (0.42) | POLQALDH1A1TRPM8MEN1KMT2A | |
| SCHEMBL28970987 | 0.78 | ALDH1A1 (0.66) | ALDH1A1TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL9360756 | 0.77 | TDP1 (0.48) | ALDH1A1TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL20166110 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TP53SMN1; SMN2LMNAHPGD | |
| SCHEMBL6136294 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TP53SMN1; SMN2LMNAMEN1 | |
| SCHEMBL9360739 | 0.75 | NPY5R (0.50) | SMN1; SMN2PPARGPPARAFFAR1 | |
| SCHEMBL9222220 | 0.73 | CES2 (0.48) | ALDH1A1TP53SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415185-B1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1994-12-07 | — | — | EP | disclosed |
| EP-0415185-A1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |