SCHEMBL9357973

SCHEMBL9357973

CCCCO[SiH2][SiH2]OCCC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
TSHR P16473 5/20 0.36
CYP3A4 P08684 2/20 0.36
ALDH1A1 P00352 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
ATM Q13315 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28606407 0.83
SCHEMBL3299007 0.82 ADRB2 (0.41) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL705064 0.75 ADRB2 (0.45) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL705196 0.73
Butane SCHEMBL16827219 0.73 ADRB2 (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
Hydrochloric Acid SCHEMBL10569892 0.73 ADRB2 (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
Bromide SCHEMBL9709838 0.73 ADRB2 (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL2205138 0.72 THRB (0.42) TSHRCA1CA2THRB
SCHEMBL8731693 0.71
SCHEMBL18037830 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447905-B1 Transition metal component for a Ziegler catalyst system and its use BASF AG (DE) 1994-11-02 EP disclosed
EP-0447904-B1 Transition metal component for a Ziegler catalyst system and its use BASF AG (DE) 1994-10-26 EP disclosed
EP-0447959-B1 Transition metal catalyst component for a Ziegler catalytic system and its use BASF AG (DE) 1994-10-12 EP disclosed
US-5143881-A Polymerization catalysts BASF AKTIENGESELLSCHAFT (DE) 1992-09-01 US disclosed
EP-0447905-A1 Transition metal component for a Ziegler catalyst system and its use BASF Aktiengesellschaft (DE) 1991-09-25 EP disclosed
EP-0447960-A2 Transition metal component for a Ziegler catalytic system and its use BASF Aktiengesellschaft (DE) 1991-09-25 EP disclosed
EP-0447959-A2 Transition metal catalyst component for a Ziegler catalytic system and its use BASF Aktiengesellschaft (DE) 1991-09-25 EP disclosed
EP-0447904-A1 Transition metal component for a Ziegler catalyst system and its use BASF Aktiengesellschaft (DE) 1991-09-25 EP disclosed