Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | IAPP | P10997 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358181 | 1.00 | RXRA (0.57) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9362271 | 1.00 | RXRA (0.57) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9362039 | 1.00 | RXRA (0.57) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9362102 | 0.99 | RXRA (0.58) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9357921 | 0.95 | RXRA (0.56) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9357708 | 0.92 | RXRA (0.49) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9357818 | 0.92 | RXRA (0.49) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9357859 | 0.87 | RXRA (0.72) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9358171 | 0.87 | RXRA (0.72) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9681564 | 0.87 | RXRA (0.72) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470832-B1 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI CHEMICAL IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |