Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.72 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357859 | 1.00 | RXRA (0.72) | RXRATHRATHRBLTB4RCYP1A2 | |
| SCHEMBL9358171 | 1.00 | RXRA (0.72) | RXRATHRATHRBLTB4RCYP1A2 | |
| SCHEMBL9362319 | 0.95 | RXRA (0.71) | RXRATHRATHRBLTB4RCYP1A2 | |
| SCHEMBL9679355 | 0.91 | RXRA (0.63) | RXRALTB4RCNR1CNR2LMNA | |
| SCHEMBL9679804 | 0.89 | RXRA (0.59) | RXRALTB4R | |
| SCHEMBL9358181 | 0.87 | RXRA (0.57) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9358161 | 0.87 | RXRA (0.57) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9362039 | 0.87 | RXRA (0.57) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9362271 | 0.87 | RXRA (0.57) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL8984893 | 0.86 | RXRA (0.56) | RXRATHRATHRBLTB4RCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |