Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358706 | 1.00 | ABCB1 (0.46) | ABCB1ABCC9 | |
| SCHEMBL9358699 | 1.00 | ABCB1 (0.46) | ABCB1ABCC9 | |
| SCHEMBL9581474 | 0.79 | ABCB1 (0.37) | ABCB1ABCC9 | |
| SCHEMBL9581465 | 0.79 | ABCB1 (0.37) | ABCB1ABCC9 | |
| SCHEMBL9581471 | 0.79 | ABCB1 (0.37) | ABCB1ABCC9 | |
| SCHEMBL7478016 | 0.77 | ABCC9 (0.59) | ABCC9 | |
| SCHEMBL7478011 | 0.77 | ABCC9 (0.59) | ABCC9 | |
| SCHEMBL7478001 | 0.77 | ABCC9 (0.59) | ABCC9 | |
| SCHEMBL9363912 | 0.77 | KCNA5 (0.49) | ABCB1ABCC9 | |
| SCHEMBL9581711 | 0.77 | IDO1 (0.40) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426379-B1 | Substituted cyclobutenedione compounds | BEECHAM GROUP PLC (GB) | 1994-12-21 | — | — | EP | disclosed |
| US-5147866-A | Hypotensive, bronchodilator agents | BEECHAM GROUP P.L.C. (GB) | 1992-09-15 | — | — | US | disclosed |