Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581474 | 1.00 | ABCB1 (0.37) | ABCB1KCNE1KCNQ1KDM4EALDH1A1 | |
| SCHEMBL9581465 | 1.00 | ABCB1 (0.37) | ABCB1KCNE1KCNQ1KDM4EALDH1A1 | |
| SCHEMBL9197856 | 0.80 | HTR1A (0.39) | ABCB1KCNE1KCNQ1KDM4EGAA | |
| SCHEMBL9197846 | 0.80 | HTR1A (0.39) | ABCB1KCNE1KCNQ1KDM4EGAA | |
| SCHEMBL9197844 | 0.80 | HTR1A (0.39) | ABCB1KCNE1KCNQ1KDM4EGAA | |
| SCHEMBL9358706 | 0.79 | ABCB1 (0.46) | ABCB1ABCC9 | |
| SCHEMBL9358694 | 0.79 | ABCB1 (0.46) | ABCB1ABCC9 | |
| SCHEMBL9358699 | 0.79 | ABCB1 (0.46) | ABCB1ABCC9 | |
| SCHEMBL9581706 | 0.79 | IDO1 (0.40) | ABCB1KCNE1KCNQ1KDM4EL3MBTL1 | |
| SCHEMBL9581711 | 0.79 | IDO1 (0.40) | ABCB1KCNE1KCNQ1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210234-A | Benzopyran intermediates | BEECHAM GROUP P.L.C. (GB) | 1993-05-11 | — | — | US | disclosed |
| EP-0250077-B1 | PHARMACOLOGICALLY ACTIVE BENZOPYRANES | BEECHAM GROUP PLC (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-5075460-A | Hypotensive agents | BEECHAM GROUP PLC (GB) | 1991-12-24 | — | — | US | disclosed |
| US-4943582-A | Active compounds | BEECHAM GROUP P.L.C. (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0250077-A2 | Pharmacologically active benzopyranes | BEECHAM GROUP PLC (GB) | 1987-12-23 | — | — | EP | disclosed |