Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935687 | 0.91 | PIK3CD (0.38) | PIK3CDPIK3R1PIK3CGPIK3CBTP53 | |
| SCHEMBL14744075 | 0.84 | PIK3CD (0.43) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3R2 | |
| SCHEMBL14743894 | 0.83 | PIK3CD (0.42) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3R2 | |
| SCHEMBL14744225 | 0.82 | PIK3CD (0.43) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3R2 | |
| SCHEMBL935114 | 0.81 | PIK3CD (0.39) | PIK3CDPIK3R1PIK3CGPIK3CBTP53 | |
| SCHEMBL4416463 | 0.80 | PIK3CD (0.55) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3R2 | |
| SCHEMBL31594490 | 0.80 | PIK3CD (0.55) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3R2 | |
| SCHEMBL4416459 | 0.80 | PIK3CD (0.55) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3R2 | |
| SCHEMBL15820628 | 0.79 | PIK3CD (0.53) | PIK3CDPIK3R1PIK3CGPIK3CBPIK3R2 | |
| SCHEMBL936006 | 0.78 | PIK3CD (0.39) | PIK3CDPIK3R1PIK3CGPIK3CBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456444-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011008302-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2011-01-20 | — | — | WO | disclosed |