Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874780 | 0.93 | FABP3 (0.49) | PTGDR2TBXA2RPTGDRHDAC3HDAC4 | |
| SCHEMBL9873565 | 0.90 | TBXA2R (0.51) | TBXA2RLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL9358770 | 0.90 | HDAC3 (0.52) | PTGDR2CYP2C9HDAC3HDAC4HDAC1 | |
| SCHEMBL9814947 | 0.88 | TBXAS1 (0.56) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL9362957 | 0.81 | KCNA5 (0.54) | PTGDR2LMNATAAR1HDAC3HDAC4 | |
| SCHEMBL9358763 | 0.80 | HDAC3 (0.50) | CYP2C9HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10366956 | 0.80 | HDAC3 (0.58) | PTGDR2TBXA2RHDAC3HDAC4HDAC1 | |
| SCHEMBL10373940 | 0.80 | TBXAS1 (0.63) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL9874564 | 0.80 | TBXA2R (0.53) | PTGDR2TBXA2RLMNAHDAC3HDAC4 | |
| SCHEMBL9874752 | 0.79 | TAAR1 (0.47) | PTGDR2LMNATAAR1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015657-A | Anticoagulants | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | claimed |
| EP-0371342-B1 | 2-Halogen-substituted N-indolyl sulfonic-acid amides, process for their preparation and their pharmaceutical use | BAYER AG (DE) | 1994-12-14 | — | — | EP | disclosed |
| US-5015657-A | Anticoagulants | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| EP-0371342-A1 | 2-Halogen-substituted N-indolyl sulfonic-acid amides, process for their preparation and their pharmaceutical use | BAYER AG (DE) | 1990-06-06 | — | — | EP | disclosed |