Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784656 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL9358757 | 0.88 | EDNRB (0.42) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL8786825 | 0.87 | MEN1 (0.54) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL9358921 | 0.87 | POLB (0.53) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL9359224 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL8538348 | 0.80 | PGR (0.42) | ALDH1A1KDM4EMEN1POLBKMT2A | |
| SCHEMBL9358956 | 0.80 | MEN1 (0.53) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL9042136 | 0.80 | MEN1 (0.46) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL15154629 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL9358761 | 0.78 | CSF1R (0.62) | ALDH1A1MEN1POLBKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421456-B1 | Quinoline derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5223513-A | Anticholesterol agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0421456-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |