Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359302 | 0.88 | CASP3 (0.48) | MAOBCASP3SENP8SENP7SENP6 | |
| SCHEMBL9359072 | 0.84 | MAOB (0.47) | MAOBMAOALMNAGAACTNNB1 | |
| SCHEMBL9359020 | 0.79 | TDP1 (0.49) | CASP3SENP7KMT2AMAPTNPC1 | |
| SCHEMBL9359225 | 0.78 | HTR1B (0.38) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9359262 | 0.78 | HTR1B (0.38) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9359229 | 0.78 | HTR1B (0.38) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9358383 | 0.77 | SLC6A4 (0.43) | LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9358949 | 0.76 | ESR1 (0.41) | LMNAGAAKMT2AMAPTNPC1 | |
| SCHEMBL9363320 | 0.76 | NPC1 (0.45) | LMNAGAAALDH1A1KMT2AHTT | |
| SCHEMBL9359275 | 0.76 | CA12 (0.40) | LMNAALDH1A1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363782-B1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | ERBA CARLO SPA (IT) | 1994-01-05 | — | — | EP | claimed |
| US-5272144-A | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-21 | — | — | US | claimed |
| WO-1990003965-A1 | ARYLOXY-, ARYLTHIO-, HETEROARYLOXY-, HETEROARYLTHIO-ALKENYLENE DERIVATIVES OF AMINES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-04-19 | — | — | WO | claimed |
| EP-0363782-A1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | claimed |
| EP-0363782-B1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | ERBA CARLO SPA (IT) | 1994-01-05 | — | — | EP | disclosed |
| US-5272144-A | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-21 | — | — | US | disclosed |
| WO-1990003965-A1 | ARYLOXY-, ARYLTHIO-, HETEROARYLOXY-, HETEROARYLTHIO-ALKENYLENE DERIVATIVES OF AMINES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-04-19 | — | — | WO | disclosed |
| EP-0363782-A1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | disclosed |