Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359061 | 0.81 | ALDH1A1 (0.38) | TDP1CYP1A2CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL9359075 | 0.81 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL9359099 | 0.80 | ALOX15 (0.44) | L3MBTL1GLAMRGPRX4TDP1CYP2C19 | |
| SCHEMBL9359121 | 0.80 | ALOX15 (0.44) | L3MBTL1GLAMRGPRX4TDP1CYP2C19 | |
| SCHEMBL9359117 | 0.80 | ALOX15 (0.44) | L3MBTL1GLAMRGPRX4TDP1CYP2C19 | |
| SCHEMBL9358968 | 0.80 | ALDH1A1 (0.40) | CYP2D6KMT2AALDH1A1 | |
| SCHEMBL9359339 | 0.79 | HTR1B (0.46) | MRGPRX4TDP1ATMALDH1A1 | |
| SCHEMBL9359292 | 0.76 | ALDH1A1 (0.48) | L3MBTL1TDP1CYP1A2POLBMEN1 | |
| SCHEMBL9359086 | 0.75 | KMT2A (0.41) | POLBMEN1KMT2AMAPTNPC1 | |
| Fumaric Acid SCHEMBL10475671 | 0.72 | ALDH1A1 (0.41) | POLBKMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363782-B1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | ERBA CARLO SPA (IT) | 1994-01-05 | — | — | EP | claimed |
| US-5272144-A | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-21 | — | — | US | claimed |
| WO-1990003965-A1 | ARYLOXY-, ARYLTHIO-, HETEROARYLOXY-, HETEROARYLTHIO-ALKENYLENE DERIVATIVES OF AMINES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-04-19 | — | — | WO | claimed |
| EP-0363782-A1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | claimed |
| EP-0363782-B1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | ERBA CARLO SPA (IT) | 1994-01-05 | — | — | EP | disclosed |
| US-5272144-A | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines and pharmaceutical use | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-12-21 | — | — | US | disclosed |
| WO-1990003965-A1 | ARYLOXY-, ARYLTHIO-, HETEROARYLOXY-, HETEROARYLTHIO-ALKENYLENE DERIVATIVES OF AMINES | FARMITALIA CARLO ERBA S.R.L. (IT) | 1990-04-19 | — | — | WO | disclosed |
| EP-0363782-A1 | Aryloxy-, arylthio-, heteroaryloxy-, heteroarylthio-alkenylene derivatives of amines | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-04-18 | — | — | EP | disclosed |