Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359818 | 0.87 | CACNA1F (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL9363639 | 0.86 | CACNA1D (0.41) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL6949791 | 0.86 | CACNA1F (0.46) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL9359615 | 0.85 | CACNA1F (0.40) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL6958489 | 0.84 | CACNA1D (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL9359608 | 0.84 | EPHX2 (0.41) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL8950009 | 0.82 | CACNA1F (0.46) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL9359378 | 0.81 | ADORA3 (0.47) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL6956368 | 0.78 | CACNA1F (0.40) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL9369030 | 0.74 | CACNA1F (0.49) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325129-B1 | Disubstituted pyridines | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| EP-0325129-A2 | Disubstituted pyridines | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |