Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949791 | 0.88 | CACNA1F (0.46) | BCHECACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6958489 | 0.88 | CACNA1D (0.39) | EPHX2BCHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL9359332 | 0.84 | CACNA1F (0.38) | BCHECACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9359378 | 0.83 | ADORA3 (0.47) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL9359818 | 0.83 | CACNA1F (0.42) | BCHECACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9363639 | 0.82 | CACNA1D (0.41) | CACNA1FCACNA1DCACNA1SCACNA1CCA12 | |
| SCHEMBL8949608 | 0.81 | EPHX2 (0.51) | EPHX2CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6956368 | 0.80 | CACNA1F (0.40) | BCHECACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL9359615 | 0.80 | CACNA1F (0.40) | CACNA1FCACNA1DCACNA1SCACNA1CSMN1; SMN2 | |
| SCHEMBL10518260 | 0.80 | SMN1; SMN2 (0.47) | EPHX2BCHECACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325129-B1 | Disubstituted pyridines | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| EP-0325129-A2 | Disubstituted pyridines | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |