Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CTSE | P14091 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057707 | 0.88 | TAAR1 (0.41) | LMNATAAR1CYP2D6HTR2AHRH1 | |
| SCHEMBL169508 | 0.83 | LMNA (0.56) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL9358758 | 0.83 | LMNA (0.43) | LMNACCR5TAAR1CYP2D6MIF | |
| Ammonia Solution, Strong SCHEMBL1640901 | 0.80 | LMNA (0.54) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL9359053 | 0.80 | ESR1 (0.38) | LMNACYP2D6NOS3NOS2TDP1 | |
| SCHEMBL19734401 | 0.80 | GABBR2 (0.52) | TAAR1CYP2D6HTR2AHRH1 | |
| Methylamine SCHEMBL27931105 | 0.78 | LMNA (0.52) | LMNACCR5TAAR1CYP2D6HTR2A | |
| SCHEMBL13789069 | 0.78 | LMNA (0.40) | LMNACCR5CYP2D6 | |
| SCHEMBL9358844 | 0.77 | LMNA (0.38) | LMNACCR5TAAR1CYP2D6HTR2A | |
| Hypochlorous Acid SCHEMBL11415854 | 0.76 | LMNA (0.56) | LMNACCR5TAAR1CYP2D6HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464131-B1 | INITIATORS FOR POLYMERIZATION | CIBA GEIGY AG (CH) | 1994-12-28 | — | — | EP | claimed |