Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359390 | 1.00 | OPRD1 (0.46) | OPRD1SLC6A9OPRL1OPRM1OPRK1 | |
| SCHEMBL9359394 | 1.00 | OPRD1 (0.46) | OPRD1SLC6A9OPRL1OPRM1OPRK1 | |
| SCHEMBL30616541 | 0.80 | OPRD1 (0.38) | OPRD1SLC6A9OPRL1OPRM1OPRK1 | |
| SCHEMBL25973505 | 0.78 | OPRD1 (0.46) | OPRD1SLC6A9OPRL1OPRM1OPRK1 | |
| SCHEMBL17012864 | 0.78 | OPRD1 (0.46) | OPRD1SLC6A9OPRL1OPRM1OPRK1 | |
| SCHEMBL5456237 | 0.75 | SLC6A9 (0.40) | OPRD1SLC6A9CHRM2CHRM1CHRM3 | |
| SCHEMBL5456238 | 0.75 | SLC6A9 (0.40) | OPRD1SLC6A9CHRM2CHRM1CHRM3 | |
| SCHEMBL24802139 | 0.75 | OPRD1 (0.44) | OPRD1SLC6A9OPRL1OPRM1OPRK1 | |
| SCHEMBL9363615 | 0.75 | OPRD1 (0.44) | OPRD1SLC6A9OPRL1OPRM1OPRK1 | |
| SCHEMBL5454645 | 0.75 | OPRD1 (0.44) | OPRD1SLC6A9OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406112-B1 | 1-Benzhydrylazetidines, their preparation and their use as intermediates for the preparation of compounds with antimicrobial activity | ESTEVE LABOR DR (ES) | 1994-12-28 | — | — | EP | claimed |
| US-5073646-A | Chemical intermediates, microbiocides | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1991-12-17 | — | — | US | claimed |
| EP-0406112-A1 | 1-Benzhydrylazetidines, their preparation and their use as intermediates for the preparation of compounds with antimicrobial activity | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1991-01-02 | — | — | EP | claimed |