Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530032 | 0.82 | GAA (0.60) | MTNR1AMTNR1BGRIN2BGAAL3MBTL1 | |
| SCHEMBL17530027 | 0.82 | GAA (0.60) | MTNR1AMTNR1BGRIN2BGAAL3MBTL1 | |
| SCHEMBL7336815 | 0.82 | GAA (0.60) | MTNR1AMTNR1BGRIN2BGAAL3MBTL1 | |
| SCHEMBL6955823 | 0.80 | GAA (0.44) | GAAL3MBTL1CA1CRHBPCRHR2 | |
| SCHEMBL6953679 | 0.80 | GAA (0.44) | GAAL3MBTL1CA1CRHBPCRHR2 | |
| SCHEMBL8522066 | 0.80 | CACNA1G (0.39) | CRHBPCRHR2 | |
| SCHEMBL16968736 | 0.77 | GAA (0.57) | GAAL3MBTL1CRHBPCRHR2MEN1 | |
| SCHEMBL6962537 | 0.76 | GAA (0.43) | GAAL3MBTL1CRHBPCRHR2MEN1 | |
| Hydrochloric Acid SCHEMBL6957801 | 0.75 | GAA (0.43) | GAAL3MBTL1CRHBPCRHR2MEN1 | |
| SCHEMBL8110023 | 0.73 | GABRP (0.35) | GAAL3MBTL1MAOACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385658-B1 | Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes | LILLY CO ELI (US) | 1994-12-28 | — | — | EP | claimed |