SCHEMBL9359484

SCHEMBL9359484

CC1=C(c2ccccc2)C(c2ccccc2)=C(C)[C]1c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
PDE4B Q07343 1/20 0.39
TSHR P16473 2/20 0.38
ACHE P22303 2/20 0.38
LMNA P02545 2/20 0.38
ALOX12 P18054 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
SLC22A2 O15244 1/20 0.35
SLC22A1 O15245 1/20 0.35
SLC22A3 O75751 1/20 0.35
SLC6A4 P31645 1/20 0.35
CYP2A6 P11509 1/20 0.34
CYP2B6 P20813 1/20 0.34
MAPT P10636 2/20 0.34
MITF O75030 1/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PTGS2 P35354 2/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3686927 0.82 ALDH1A1 (0.47) ALDH1A1TSHRACHELMNAALOX12
SCHEMBL7023222 0.76 ALDH1A1 (0.40) ALDH1A1PDE4BTSHRACHELMNA
SCHEMBL7258464 0.76 PDE4B (0.54) ALDH1A1PDE4BLMNAL3MBTL1MAPT
SCHEMBL6414357 0.73 ALDH1A1 (0.50) ALDH1A1PDE4BLMNASLC22A2SLC22A1
SCHEMBL4936702 0.73 ALDH1A1 (0.50) ALDH1A1PDE4BLMNASLC22A2SLC22A1
SCHEMBL532970 0.71 ALDH1A1 (0.67) ALDH1A1PDE4BLMNASLC22A2SLC22A1
SCHEMBL852224 0.71 ALDH1A1 (0.67) ALDH1A1PDE4BLMNASLC22A2SLC22A1
SCHEMBL532969 0.71 ALDH1A1 (0.67) ALDH1A1PDE4BLMNASLC22A2SLC22A1
SCHEMBL20121190 0.70 PDE4B (0.54) ALDH1A1PDE4BLMNAMAPTMITF
SCHEMBL20161110 0.70 PDE4B (0.54) ALDH1A1PDE4BLMNAMAPTMITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0345653-B1 Transition metal complex BASF AG (DE) 1994-10-26 EP disclosed
US-5103065-A TRANSITION METAL COMPLEXES AS CATALYSTS FOR HYDROGENATION HYDROFORMYLATION AND CYCLOTRIMERIZATION BASF AKTIENGESELLSCHAFT (DE) 1992-04-07 US disclosed
US-4999443-A Transition metal complexes BASF AKTIENGESELLSCHAFT (DE) 1991-03-12 US disclosed