Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040212 | 0.90 | GAA (0.56) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10365723 | 0.90 | GAA (0.56) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9628294 | 0.90 | GAA (0.56) | GAACDK1MAPTTP53GLA | |
| Nicosulfuron SCHEMBL27919803 | 0.89 | CDK1 (0.56) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9363855 | 0.88 | GAA (0.54) | GAACDK1MAPTTP53GLA | |
| Nicosulfuron SCHEMBL29440408 | 0.87 | CDK1 (0.59) | GAACDK1MAPTTP53GLA | |
| Nicosulfuron SCHEMBL22938 | 0.87 | CDK1 (0.59) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10365711 | 0.87 | GAA (0.53) | GAACDK1MAPTTP53GLA | |
| Nicosulfuron SCHEMBL8536419 | 0.87 | CDK1 (0.59) | GAACDK1MAPTTP53GLA | |
| SCHEMBL1014043 | 0.86 | GAA (0.54) | GAACDK1MAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532058-B1 | Process for preparing halogenosulfonyl-substituted pyridine compounds | ISHIHARA SANGYO KAISHA (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0298752-B1 | Mercapto-substituted pyridine compounds and process for preparing the same | ISHIHARA SANGYO KAISHA (JP) | 1994-02-02 | — | — | EP | disclosed |
| EP-0532058-A1 | Process for preparing halogenosulfonyl-substituted pyridine compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5168113-A | Intermediates for herbicides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| US-5128474-A | Herbicides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1992-07-07 | — | — | US | disclosed |