Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359710 | 1.00 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL11808597 | 0.83 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL11808595 | 0.83 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL1485801 | 0.81 | TSHR (0.48) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL18812997 | 0.79 | MEN1 (0.50) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL16655484 | 0.79 | SMN1; SMN2 (0.46) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL6206515 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL6206511 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL7093267 | 0.76 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9565749 | 0.76 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |