Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | STAT1 | P42224 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11779586 | 0.99 | MAPT (0.56) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11449360 | 0.88 | NPC1 (0.50) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11441536 | 0.88 | NPC1 (0.50) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9359760 | 0.82 | NPC1 (0.50) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL9359752 | 0.82 | NPC1 (0.50) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL5708166 | 0.81 | NPC1 (0.63) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL5708171 | 0.81 | NPC1 (0.63) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL8155474 | 0.81 | NPC1 (0.60) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11466870 | 0.81 | NPC1 (0.50) | MAPTRAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11466871 | 0.81 | NPC1 (0.50) | MAPTRAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001221-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |