Phenol

Phenol

SCHEMBL9359803

O=C1OC(c2cc(Br)c(O)c(Br)c2)(c2cc(Br)c(O)c(Br)c2)c2ccccc21.Oc1ccccc1

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.89
HSP90AA1 P07900 2/20 0.87
DHFR P00374 4/20 0.66
TYMS P04818 3/20 0.66
MAPT P10636 4/20 0.64
LMNA P02545 4/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
TDP1 Q9NUW8 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
GPR55 Q9Y2T6 2/20 0.64
ALDH1A1 P00352 1/20 0.64
ESR1 P03372 1/20 0.64
TP53 P04637 1/20 0.64
CYP3A4 P08684 1/20 0.64
ALOX15 P16050 1/20 0.64
TSHR P16473 1/20 0.64
ESR2 Q92731 1/20 0.64
HSD17B10 Q99714 1/20 0.64
PRMT1 Q99873 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL959033 1.00 AKR1C1 (0.89) AKR1C1HSP90AA1DHFRTYMSMAPT
SCHEMBL38664589 0.94 AKR1C1 (1.00) AKR1C1HSP90AA1DHFRTYMSMAPT
SCHEMBL1649630 0.94 AKR1C1 (1.00) AKR1C1HSP90AA1DHFRTYMSMAPT
SCHEMBL4445190 0.93 AKR1C1 (0.97) AKR1C1HSP90AA1DHFRTYMSMAPT
Biphenyl SCHEMBL10457275 0.92 AKR1C1 (0.89) AKR1C1HSP90AA1DHFRTYMSMAPT
Ethane SCHEMBL11224255 0.92 AKR1C1 (0.94) AKR1C1HSP90AA1DHFRTYMSMAPT
SCHEMBL11459322 0.85 AKR1C1 (0.82) AKR1C1HSP90AA1DHFRTYMSMAPT
Fluorescein SCHEMBL2585358 0.84 FTO (0.77) AKR1C1HSP90AA1DHFRTYMSMAPT
Phenolphthalein SCHEMBL3480729 0.82 MAPT (0.93) AKR1C1HSP90AA1DHFRTYMSMAPT
Phenolphthalein SCHEMBL9275181 0.82 MAPT (0.93) AKR1C1HSP90AA1DHFRTYMSMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0477105-B1 Testing device TERUMO CORP (JP) 1994-12-28 EP disclosed
US-5244631-A Platelike stick composed of water-disintegratable layer with superposed water-soluble layer and multiplicity of minute pieces of water-insoluble material, detecting function part deposited on stick surface TERUMO KABUSHIKI KAISHA (JP) 1993-09-14 US disclosed
EP-0477105-A1 Testing device TERUMO KABUSHIKI KAISHA (JP) 1992-03-25 EP disclosed
EP-0422888-A2 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1991-04-17 EP disclosed