Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 5/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9903552 | 0.98 | TET2 (0.32) | TET2TET3TET1 | |
| SCHEMBL9903551 | 0.83 | — | — | |
| SCHEMBL16093370 | 0.81 | — | — | |
| SCHEMBL9393683 | 0.78 | TET2 (0.39) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL351637 | 0.78 | TET2 (0.40) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL28667115 | 0.77 | TSHR (0.38) | ALOX15 | |
| SCHEMBL29167702 | 0.75 | — | — | |
| SCHEMBL19611128 | 0.72 | — | — | |
| SCHEMBL15147043 | 0.71 | TET2 (0.34) | TET2 | |
| SCHEMBL22615581 | 0.71 | ALOX15 (0.36) | TET2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841284-B2 | Compound having neurite-outgrowing activity | LEAD CHEMICAL CO., LTD (JP) | 2014-09-23 | — | — | US | disclosed |
| US-8841284-B2 | Compound having neurite-outgrowing activity | LEAD CHEMICAL CO., LTD (JP) | 2014-09-23 | — | — | US | disclosed |
| EP-2463292-B1 | COMPOUND HAVING NEURITE-OUTGROWING ACTIVITY | LEAD CHEM CO LTD (JP) | 2014-08-27 | — | — | EP | disclosed |
| EP-2463292-B1 | COMPOUND HAVING NEURITE-OUTGROWING ACTIVITY | LEAD CHEM CO LTD (JP) | 2014-08-27 | — | — | EP | disclosed |
| US-20120190841-A1 | COMPOUND HAVING NEURITE-OUTGROWING ACTIVITY | LEAD CHEMICAL CO., LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
| US-20120190841-A1 | COMPOUND HAVING NEURITE-OUTGROWING ACTIVITY | LEAD CHEMICAL CO., LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
| EP-2463292-A1 | COMPOUND HAVING NEURITE-OUTGROWING ACTIVITY | Lead Chemical Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011010364-A1 | COMPOUND HAVING NEURITE-OUTGROWING ACTIVITY | リードケミカル株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190841-A1 | COMPOUND HAVING NEURITE-OUTGROWING ACTIVITY | GRIN2C, GRIN2B, GFRA2 | TET2 4811/4885TET3 4728/4885TET1 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.