Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956911 | 0.91 | GAA (0.61) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL4661270 | 0.91 | GAA (0.61) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL2108301 | 0.85 | GAA (0.54) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL4296577 | 0.85 | GAA (0.54) | GAAKMT2APKMBCL9CTNNB1 | |
| Ammonia Solution, Strong SCHEMBL9436280 | 0.83 | GAA (0.53) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL17695797 | 0.83 | GAA (0.57) | GAAKMT2APKMBCL9CTNNB1 | |
| Ammonia Solution, Strong SCHEMBL9436297 | 0.83 | GAA (0.53) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL12858124 | 0.83 | ACHE (0.60) | GAAKMT2APKMBCL9CTNNB1 | |
| Acrylamide SCHEMBL28309906 | 0.82 | GAA (0.51) | GAAKMT2APKMBCL9CTNNB1 | |
| SCHEMBL11973529 | 0.81 | GAA (0.58) | GAAKMT2APKMBCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |