Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14195848 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL3906365 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL14195852 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL14195849 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL14195854 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL11765947 | 0.94 | ALDH1A1 (0.63) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL9719099 | 0.90 | ALDH1A1 (0.68) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL9122728 | 0.90 | FDPS (0.49) | ALDH1A1MAPK1MEN1KMT2ATHRB | |
| SCHEMBL7829405 | 0.90 | FDPS (0.49) | ALDH1A1MAPK1MEN1KMT2ATHRB | |
| SCHEMBL8772656 | 0.90 | FDPS (0.49) | ALDH1A1MAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351725-B2 | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists | MERCK & CO., INC. (US) | 2008-04-01 | — | — | US | disclosed |
| US-7351725-B2 | N-(benzyl)aminoalkylcarboxylates, phosphinates, phosphonates and tetrazoles as Edg receptor agonists | MERCK & CO., INC. (US) | 2008-04-01 | — | — | US | disclosed |
| EP-0492484-B1 | Substituted N-[phenyl-(thioxomethyl)]-morpholine derivatives, a process for preparing them as well as compositions containing these compounds and the use of them | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1994-11-09 | — | — | EP | disclosed |
| US-5254547-A | Thioacid amide derivatives and fodder compositions containing the same | EGIS GYOGYSZERGYAR (HU) | 1993-10-19 | — | — | US | disclosed |
| CN-1062728-A | Thioamide derivatives and the feed composition that contains thioamide derivatives | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1992-07-15 | — | — | CN | disclosed |
| EP-0492484-A1 | Substituted N-[phenyl-(thioxomethyl)]-morpholine derivatives, a process for preparing them as well as compositions containing these compounds and the use of them | EGIS GYOGYSZERGYAR (HU) | 1992-07-01 | — | — | EP | disclosed |