Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180421 | 0.85 | AKR1C3 (0.48) | MCL1AKR1C3AKR1C2HSD17B10CYP3A4 | |
| SCHEMBL8637909 | 0.84 | AKR1C3 (0.52) | MCL1AKR1C3AKR1C2HSD17B10CYP3A4 | |
| SCHEMBL29740644 | 0.84 | AKR1C3 (0.52) | MCL1AKR1C3AKR1C2HSD17B10CYP3A4 | |
| SCHEMBL29740639 | 0.82 | AKR1C3 (0.45) | MCL1AKR1C3AKR1C2HSD17B10CYP3A4 | |
| SCHEMBL21551821 | 0.82 | AKR1C3 (0.45) | MCL1AKR1C3AKR1C2HSD17B10CYP3A4 | |
| SCHEMBL9702114 | 0.81 | CYP3A4 (0.67) | MCL1AKR1C3AKR1C2HSD17B10CYP3A4 | |
| SCHEMBL2122382 | 0.80 | MCL1 (0.57) | MCL1AKR1C3AKR1C2HSD17B10CYP3A4 | |
| SCHEMBL26224853 | 0.78 | ALDH1A1 (0.46) | AKR1C3AKR1C2HSD17B10CYP3A4ALOX15 | |
| SCHEMBL9653127 | 0.78 | CYP3A4 (0.44) | MCL1AKR1C3AKR1C2HSD17B10CYP3A4 | |
| SCHEMBL9361517 | 0.76 | SLC6A4 (0.40) | HSD17B10CYP3A4ALOX15TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |