Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.50 |
| ▸ | HRH1 | P35367 | 6/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22252849 | 0.78 | ACHE (0.78) | ACHEADRA1AADRA1BHRH1DRD2 | |
| SCHEMBL16227246 | 0.77 | ACHE (0.68) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7395278 | 0.76 | ACHE (0.69) | ACHEADRA1AADRA1BHRH1DRD2 | |
| SCHEMBL16226783 | 0.76 | ACHE (0.69) | ACHEADRA1AADRA1BHRH1DRD2 | |
| SCHEMBL9360735 | 0.75 | DRD2 (0.45) | ACHEADRA1AADRA1BALOX5HRH1 | |
| SCHEMBL9360297 | 0.74 | ACHE (0.53) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL9249869 | 0.74 | ACHE (0.68) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL22252679 | 0.74 | ACHE (0.88) | ACHEADRA1AADRA1BHRH1DRD2 | |
| SCHEMBL21663684 | 0.74 | DRD2 (0.56) | ACHEADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL22252847 | 0.73 | ACHE (0.66) | ACHEADRA1AADRA1BHRH1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |