Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364738 | 0.76 | MAPK1 (0.46) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9361507 | 0.73 | MAPK1 (0.46) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL5212814 | 0.72 | MAPK1 (0.71) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL3613332 | 0.70 | ALDH1A1 (0.46) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL8676657 | 0.70 | MAPK1 (0.60) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL28975051 | 0.69 | MAPK1 (0.47) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL10596845 | 0.68 | MAPK1 (0.57) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9365438 | 0.68 | MAPK1 (0.46) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| Dipyrocetyl SCHEMBL29508594 | 0.66 | MAPK1 (1.00) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| Dipyrocetyl SCHEMBL26164 | 0.66 | MAPK1 (1.00) | MAPK1KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241901-B1 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5061794-A | Effective against pseudomonads | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0241901-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-10-21 | — | — | EP | disclosed |