Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.63 |
| ▸ | BACE1 | P56817 | 3/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.47 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356386 | 1.00 | APP (0.63) | APPBACE1NR1H4PTGS1PTGS2 | |
| SCHEMBL9360432 | 1.00 | APP (0.63) | APPBACE1NR1H4PTGS1PTGS2 | |
| SCHEMBL9356392 | 1.00 | APP (0.63) | APPBACE1NR1H4PTGS1PTGS2 | |
| Cordiachromene A SCHEMBL9356402 | 0.93 | PTGS1 (0.68) | APPBACE1NR1H4PTGS1PTGS2 | |
| Cordiachromene A SCHEMBL16666288 | 0.93 | PTGS1 (0.68) | APPBACE1NR1H4PTGS1PTGS2 | |
| Cordiachromene A SCHEMBL16666262 | 0.93 | PTGS1 (0.68) | APPBACE1NR1H4PTGS1PTGS2 | |
| SCHEMBL10536271 | 0.84 | PTGS1 (0.60) | APPBACE1NR1H4PTGS1PTGS2 | |
| SCHEMBL14212077 | 0.82 | ALOX5 (0.87) | APPBACE1NR1H4PTGS1ALOX5 | |
| Elaeagin SCHEMBL29754176 | 0.81 | PTGS1 (0.61) | APPBACE1NR1H4PTGS1PTGS2 | |
| Confluentin SCHEMBL31544928 | 0.77 | APP (1.00) | APPBACE1NR1H4PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304842-A2 | Isoprenoid derivatives and anti-ulcer agents containing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-03-01 | — | — | EP | claimed |
| EP-0304842-B1 | Isoprenoid derivatives and anti-ulcer agents containing the same | NISSHIN FLOUR MILLING CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-4906669-A | Isoprenoid derivatives and anti-ulcer agents containing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0304842-A2 | Isoprenoid derivatives and anti-ulcer agents containing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |