Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360522 | 1.00 | LMNA (0.49) | LMNACYP1A2TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL9360971 | 0.95 | LMNA (0.47) | LMNACYP1A2TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL9360965 | 0.95 | LMNA (0.47) | LMNACYP1A2TSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL9364802 | 0.93 | LMNA (0.48) | LMNATSHRSMN1; SMN2ESR1KDM4E | |
| SCHEMBL9364799 | 0.93 | LMNA (0.48) | LMNATSHRSMN1; SMN2ESR1KDM4E | |
| SCHEMBL9364863 | 0.88 | APP (0.46) | LMNATSHRSMN1; SMN2ESR1KDM4E | |
| SCHEMBL9364856 | 0.88 | APP (0.46) | LMNATSHRSMN1; SMN2ESR1KDM4E | |
| SCHEMBL9360595 | 0.88 | MAPT (0.49) | LMNACYP1A2SMN1; SMN2ESR1KDM4E | |
| SCHEMBL9360589 | 0.88 | MAPT (0.49) | LMNACYP1A2SMN1; SMN2ESR1KDM4E | |
| SCHEMBL9360957 | 0.85 | KDM4E (0.54) | LMNACYP2C19CYP2D6KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335641-B1 | Organic nonlinear optical substance | TEIJIN LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5196147-A | Optical crystals | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0335641-A2 | Organic nonlinear optical substance | TEIJIN LIMITED (JP) | 1989-10-04 | — | — | EP | disclosed |