Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364802 | 1.00 | LMNA (0.48) | LMNAALDH1A1ESR1CHRM1TSHR | |
| SCHEMBL9364856 | 0.95 | APP (0.46) | LMNAALDH1A1ESR1CHRM1TSHR | |
| SCHEMBL9364863 | 0.95 | APP (0.46) | LMNAALDH1A1ESR1CHRM1TSHR | |
| SCHEMBL9360522 | 0.93 | LMNA (0.49) | LMNAALDH1A1ESR1TSHRTDP1 | |
| SCHEMBL9360513 | 0.93 | LMNA (0.49) | LMNAALDH1A1ESR1TSHRTDP1 | |
| SCHEMBL9360595 | 0.90 | MAPT (0.49) | LMNAALDH1A1ESR1TDP1MCL1 | |
| SCHEMBL9360589 | 0.90 | MAPT (0.49) | LMNAALDH1A1ESR1TDP1MCL1 | |
| SCHEMBL9360965 | 0.89 | LMNA (0.47) | LMNAALDH1A1ESR1TSHRTDP1 | |
| SCHEMBL9360971 | 0.89 | LMNA (0.47) | LMNAALDH1A1ESR1TSHRTDP1 | |
| SCHEMBL9360803 | 0.85 | APP (0.48) | LMNAALDH1A1ESR1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335641-B1 | Organic nonlinear optical substance | TEIJIN LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5196147-A | Optical crystals | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |