Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.61 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360681 | 1.00 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPTMITFTP53 | |
| SCHEMBL9360889 | 0.84 | MAPT (0.62) | ALDH1A1MAPTKDM4ECISD1SLC16A3 | |
| SCHEMBL9360892 | 0.84 | MAPT (0.62) | ALDH1A1MAPTKDM4ECISD1SLC16A3 | |
| SCHEMBL4600830 | 0.83 | EGFR (0.85) | ALDH1A1KDM4ECISD1SLC16A3CYP3A4 | |
| SCHEMBL10413058 | 0.83 | EGFR (0.85) | ALDH1A1KDM4ECISD1SLC16A3CYP3A4 | |
| SCHEMBL4600832 | 0.83 | EGFR (0.85) | ALDH1A1KDM4ECISD1SLC16A3CYP3A4 | |
| SCHEMBL9362059 | 0.82 | MCL1 (0.50) | ALDH1A1LMNAMAPTMITFTP53 | |
| SCHEMBL9362053 | 0.82 | MCL1 (0.50) | ALDH1A1LMNAMAPTMITFTP53 | |
| SCHEMBL6841774 | 0.82 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTMITFTP53 | |
| SCHEMBL22691968 | 0.82 | EGFR (0.71) | ALDH1A1KDM4ECISD1SLC16A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335641-B1 | Organic nonlinear optical substance | TEIJIN LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5196147-A | Optical crystals | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0335641-A2 | Organic nonlinear optical substance | TEIJIN LIMITED (JP) | 1989-10-04 | — | — | EP | disclosed |