Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362053 | 1.00 | MCL1 (0.50) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL9361399 | 0.95 | APP (0.57) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL9361403 | 0.95 | APP (0.57) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL9360595 | 0.85 | MAPT (0.49) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL9360589 | 0.85 | MAPT (0.49) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL9508065 | 0.85 | MCL1 (0.65) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL9364799 | 0.83 | LMNA (0.48) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL9364802 | 0.83 | LMNA (0.48) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL6375833 | 0.83 | MCL1 (0.52) | MCL1APPLMNAMAPTALDH1A1 | |
| SCHEMBL6375831 | 0.83 | MCL1 (0.52) | MCL1APPLMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335641-B1 | Organic nonlinear optical substance | TEIJIN LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5196147-A | Optical crystals | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0335641-A2 | Organic nonlinear optical substance | TEIJIN LIMITED (JP) | 1989-10-04 | — | — | EP | disclosed |