Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559559 | 0.89 | TSHR (0.58) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| Diethyl Phthalate SCHEMBL30147367 | 0.84 | TSHR (0.60) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| Diethyl Phthalate SCHEMBL8873370 | 0.84 | TSHR (0.60) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| SCHEMBL9379355 | 0.84 | TSHR (0.88) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| SCHEMBL31009568 | 0.84 | TSHR (0.88) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| SCHEMBL4463531 | 0.83 | TSHR (0.72) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| SCHEMBL14958374 | 0.79 | TSHR (0.66) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| Diethyl Phthalate SCHEMBL22296 | 0.79 | TSHR (1.00) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| Diethyl Phthalate SCHEMBL29404255 | 0.79 | TSHR (1.00) | TSHRCDC25BALDH1A1HSD17B10TDP1 | |
| Diethyl Phthalate SCHEMBL5306972 | 0.79 | TSHR (1.00) | TSHRCDC25BALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407808-B1 | Catalyst, process for preparation of same, and process for polymerization of olefins using same | SHOWA DENKO KK (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5208302-A | Coordination Catalysts Containing a Ketoester, Stereoregular | SHOWA DENKO K.K. (JP) | 1993-05-04 | — | — | US | disclosed |
| US-5049533-A | Titanium, magnesium, halogen, keto-ester 7 | SHOWA DENKO K.K. (JP) | 1991-09-17 | — | — | US | disclosed |
| EP-0407808-A2 | Catalyst, process for preparation of same, and process for polymerization of olefins using same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-01-16 | — | — | EP | disclosed |