Diethyl Phthalate

Diethyl Phthalate

SCHEMBL8873370

CCOC(=O)c1ccccc1C(=O)OCC.CCc1ccc(C(=O)O)c(C(=O)O)c1CC

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.60
CDC25B P30305 1/20 0.49
ALDH1A1 P00352 4/20 0.49
HSD17B10 Q99714 1/20 0.49
ADORA3 P0DMS8 3/20 0.45
KMT2A Q03164 2/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP3A4 P08684 2/20 0.43
LMNA P02545 1/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPK10 P53779 1/20 0.43
PTK2B Q14289 1/20 0.43
NCOA1 Q15788 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethyl Phthalate SCHEMBL30147367 1.00 TSHR (0.60) TSHRCDC25BALDH1A1HSD17B10ADORA3
Phthalic Acid SCHEMBL29429444 0.88 ALDH1A1 (0.48) CDC25BALDH1A1HSD17B10KMT2ATDP1
Phthalic Acid SCHEMBL10963447 0.88 ALDH1A1 (0.48) CDC25BALDH1A1HSD17B10KMT2ATDP1
Dibutyl Phthalate SCHEMBL29658281 0.87 TSHR (0.64) TSHRALDH1A1HSD17B10MAPTTDP1
SCHEMBL29658282 0.86 LMNA (0.42) TSHRCDC25BALDH1A1HSD17B10KMT2A
Toluic Acid SCHEMBL11277682 0.85 CYP3A4 (0.43) TSHRALDH1A1HSD17B10KMT2ACYP3A4
SCHEMBL75798 0.84 ALDH1A1 (0.41) TSHRALDH1A1KMT2AMAPTTDP1
SCHEMBL29672069 0.84 TSHR (0.62) TSHRCDC25BALDH1A1HSD17B10KMT2A
SCHEMBL9360737 0.84 TSHR (0.62) TSHRCDC25BALDH1A1HSD17B10KMT2A
SCHEMBL28222952 0.83 TSHR (0.57) TSHRCDC25BALDH1A1HSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5600958-A Shipper HENNING STEVE (US) 1997-02-11 US disclosed