Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 11/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421255 | 0.93 | TSHR (0.56) | TSHRMEN1KMT2ATHRBFAAH | |
| SCHEMBL11964784 | 0.86 | THRB (0.52) | TSHRMEN1KMT2ATHRBFAAH | |
| SCHEMBL28536003 | 0.85 | TSHR (0.54) | TSHRMEN1KMT2ATHRBFAAH | |
| SCHEMBL16385235 | 0.85 | TSHR (0.62) | TSHRTHRBACHEPOLBAPEX1 | |
| SCHEMBL16309328 | 0.85 | TSHR (0.62) | TSHRTHRBACHEPOLBAPEX1 | |
| SCHEMBL2720550 | 0.85 | TSHR (0.62) | TSHRTHRBACHEPOLBAPEX1 | |
| SCHEMBL16384917 | 0.85 | TSHR (0.62) | TSHRTHRBACHEPOLBAPEX1 | |
| SCHEMBL29100282 | 0.83 | TSHR (0.61) | TSHRTHRBACHEPOLBAPEX1 | |
| SCHEMBL29100295 | 0.83 | TSHR (0.61) | TSHRTHRBACHEPOLBAPEX1 | |
| SCHEMBL21301444 | 0.83 | TSHR (0.53) | TSHRTHRBFAAHACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394787-B1 | Compositions containing carbamide group containing (meth)acrylic acid esters for use as adhesive components for the treatment of collagenic materials in medicine, and preparation of the compositions | BAYER AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| US-5300537-A | Bonding dental fillings | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |