Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 10/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 10/20 | 0.50 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520538 | 0.86 | PPID (0.47) | TAS1R3TAS1R1BIRC2POLB | |
| SCHEMBL14163020 | 0.81 | BIRC2 (0.58) | TAS1R3TAS1R1BIRC2POLBFOLH1 | |
| SCHEMBL9364701 | 0.81 | ALDH1A1 (0.62) | FOLH1 | |
| SCHEMBL17208365 | 0.81 | BIRC2 (0.58) | TAS1R3TAS1R1BIRC2POLBFOLH1 | |
| SCHEMBL7098405 | 0.80 | TAS1R3 (0.49) | TAS1R3TAS1R1BIRC2POLBFOLH1 | |
| SCHEMBL27412717 | 0.80 | TAS1R3 (0.49) | TAS1R3TAS1R1BIRC2POLBFOLH1 | |
| SCHEMBL9361228 | 0.80 | BIRC2 (0.50) | TAS1R3TAS1R1BIRC2POLBFOLH1 | |
| SCHEMBL2462316 | 0.80 | ITGB1 (0.43) | TAS1R3TAS1R1 | |
| SCHEMBL15450546 | 0.79 | TAS1R3 (0.51) | TAS1R3TAS1R1BIRC2POLBFOLH1 | |
| SCHEMBL23616324 | 0.79 | TAS1R3 (0.58) | TAS1R3TAS1R1BIRC2POLBFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400499-B1 | Medicine containing acylaminoacid derivatives and dietetic products | KALI CHEMIE AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5089492-A | For nitrogen metabolism disturbances | KALI-CHEMIE AG (DE) | 1992-02-18 | — | — | US | disclosed |
| EP-0400499-A2 | Medicine containing acylaminoacid derivatives and dietetic products | Kali-Chemie Aktiengesellschaft (DE) | 1990-12-05 | — | — | EP | disclosed |