Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.59 |
| ▸ | THRB | P10828 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583373 | 0.95 | THRA (0.52) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL5492191 | 0.89 | PTPN11 (0.64) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL7820620 | 0.89 | PTPN11 (0.64) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL30903553 | 0.89 | PTPN11 (0.57) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL1964738 | 0.89 | PTPN11 (0.57) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL30903552 | 0.89 | PTPN11 (0.57) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL30084732 | 0.88 | NPC1 (0.54) | THRATHRBNR5A1 | |
| SCHEMBL2489105 | 0.88 | NPC1 (0.54) | THRATHRBNR5A1 | |
| SCHEMBL19549621 | 0.86 | MAOA (0.60) | THRATHRBTP53TSHRPTPN11 | |
| SCHEMBL7516526 | 0.86 | THRA (0.62) | THRATHRBTP53TSHRPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431755-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-01-26 | — | — | EP | disclosed |
| US-5152983-A | Mixture of 1,3-propanedione, 1-(4-methoxy-5-benzofurnyl)-3-phenyl and a carrier for topical application to human skin or hair | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0431755-A1 | Cosmetic composition | UNILEVER PLC (GB) | 1991-06-12 | — | — | EP | disclosed |