SCHEMBL9360895

SCHEMBL9360895

C=Cc1ccc(C2=NC(c3ccccc3)(c3ccccc3)C(=O)O2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
TSHR P16473 1/20 0.36
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
BACE1 P56817 2/20 0.33
BACE2 Q9Y5Z0 2/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
THRB P10828 1/20 0.33
CYP2C9 P11712 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9360931 0.78 POLB (0.40) ALDH1A1TSHRMAPTHPGDKMT2A
SCHEMBL9823653 0.75 BACE1 (0.39) ALDH1A1TSHRKMT2AMEN1BACE1
SCHEMBL9359842 0.72 MEN1 (0.35) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL19813889 0.72 MEN1 (0.33) ALDH1A1MAPTKMT2AMEN1POLB
SCHEMBL9364704 0.69 APP (0.32) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL6827479 0.68 BACE1 (0.43) KMT2ABACE1BACE2LMNAGLA
SCHEMBL9360045 0.66 ALDH1A1 (0.38) ALDH1A1TSHRMAPTKMT2AMEN1
SCHEMBL24241764 0.64 MAPT (0.44) ALDH1A1MAPTHPGDKMT2AMEN1
SCHEMBL2997715 0.64 ALDH1A1 (0.68) ALDH1A1TSHRMAPTMAPK1POLB
SCHEMBL447854 0.64 ALDH1A1 (0.68) ALDH1A1TSHRMAPTMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463520-B1 2-(4-Alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORP (US) 1994-12-28 EP disclosed
EP-0463520-A1 2-(4-Alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORPORATION (US) 1992-01-02 EP disclosed
US-5039813-A 2-(4-alkenylphenyl)-5-oxazolones and polymers thereof POLAROID CORPORATION (US) 1991-08-13 US disclosed