Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969972 | 0.80 | BACE1 (0.33) | BACE1BACE2LMNACYP2C9KMT2A | |
| SCHEMBL9823594 | 0.78 | TDP1 (0.32) | — | |
| SCHEMBL9360895 | 0.75 | ALDH1A1 (0.36) | BACE1BACE2LMNACYP2C9KMT2A | |
| SCHEMBL6827479 | 0.74 | BACE1 (0.43) | BACE1BACE2LMNACYP2C9KMT2A | |
| SCHEMBL9823704 | 0.73 | LMNA (0.34) | BACE1LMNA | |
| SCHEMBL508522 | 0.70 | BACE1 (0.37) | BACE1BACE2LMNACYP2C9KMT2A | |
| SCHEMBL9482559 | 0.69 | BACE1 (0.39) | BACE1BACE2LMNACYP2C9KMT2A | |
| SCHEMBL7955067 | 0.68 | ELANE (0.36) | BACE1LMNA | |
| SCHEMBL4076689 | 0.61 | BACE1 (0.40) | BACE1BACE2LMNACYP2C9KMT2A | |
| SCHEMBL11469864 | 0.60 | CFTR (0.39) | BACE1BACE2LMNACYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981933-A | Azlactone copolymers | POLAROID CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4699843-A | Azlactone-containing pressure-sensitive adhesives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0128731-B1 | AZLACTONE-CONTAINING PRESSURE-SENSITIVE ADHESIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4619867-A | WITH ACRYLIC-FUNCTIONAL CARBOXYLIC ACID, AND ACRYLIC MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0128731-A1 | Azlactone-containing pressure-sensitive adhesives | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |